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  • Gumma (pathology) - Wikipedia
    Gummas are most commonly found in the liver (gumma hepatis), but can also be found in brain, heart, skin, bone, testis, and other tissues, leading to a variety of potential problems including neurological disorders or heart valve disease
  • What Is a Gumma in Syphilis? Symptoms and Treatment
    A gumma is a distinctive, soft, tumor-like growth resulting from a specific inflammatory response against persistent Treponema pallidum Pathologically, it is a granuloma—a collection of immune cells attempting to wall off the infection
  • Cerebral Syphilitic Gumma | New England Journal of Medicine
    Cerebral Syphilitic Gumma Authors: Ke Xiao, M D https: orcid org 0000-0002-4475-5865, and Ying Si, M D Author Info Affiliations Published May 9, 2026 N Engl J Med 2026;394: 1939
  • Gumma: MedlinePlus Medical Encyclopedia
    A gumma is a soft, tumor-like growth of the tissues (granuloma) that occurs in people with syphilis
  • Syphilis Gumma: Pictures, Symptoms, Diagnosis, and Prevention - STD . . .
    Gumma syphilis is a serious manifestation of late-stage syphilis, characterized by the formation of soft, tumor-like growths that can affect various organs and tissues
  • Syphilis - DermNet
    The untreated infection can lead to endarteritis, and complications include gumma, cardiovascular, and neurological disease A gumma is a solitary granulomatous lesion with central necrosis
  • Gumma | pathology | Britannica
    gumma, soft, granulomatous, tumourlike mass, sometimes appearing during the late stages of syphilis, that occurs most often beneath the skin and mucous membranes but that may also be found in the bones, nervous system, and other organs and tissues
  • Gumma Syphilis: Causes, Symptoms, and Treatment
    A gumma represents a distinct manifestation of late-stage syphilis, a chronic bacterial infection caused by Treponema pallidum These formations are soft, non-cancerous inflammatory masses, often described as granulomatous lesions
  • Gumma of Syphilis | What Is Gumma? | Everlywell
    Late stage syphilis can cause tumor-like growths known as gummas Discover more about gumma of syphilis including causes, treatment, and prevention
  • Tertiary Syphilis - STI Treatment Guidelines
    Tertiary syphilis refers to gummas, cardiovascular syphilis, psychiatric manifestations (e g , memory loss or personality changes), or late neurosyphilis Guidelines for all forms of neurosyphilis (e g , early or late neurosyphilis) are discussed elsewhere in these recommendations (see Neurosyphilis, Ocular Syphilis, and Otosyphilis) Persons with gummas and cardiovascular syphilis who are not





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