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  • MTHFR, SHMT and folinic acid? - Phoenix Rising ME CFS Forums
    It seemed to me that SHMT + + shouldn't be that big a problem because of this second pathway But, as Valentijn points out, there is research to say that it's a problem if you are C677T compromise There is no research on the combination I was interested in: SHMT and MTHFR A1296C If you come across any studies about it, please pass it on!
  • SHMT mutations and whether to address - Phoenix Rising ME CFS Forums
    SHMT is responsible for creating methylfolate and folinic acid, so it's possible you might be needing a bit of those Hmm, I am homozygous CC for SHMT1 rs9909104 Only 4% of Europeans have that And Watsonbell --- Valentijn, is there any reason to take both folinic acid and methylfolate as supplements?
  • SHMT (+ -) while being MTHFR c677t (+ +) supplementation?
    For SHMT, my doctor recommended SHMT Spray (or the individual components: hydroxy B12, folinic acid, lactoferrin, and nucleotides) and Ultimate B (or another B-complex) She said I may need to use the SHMT RNA later on, but it probably won't be necessary
  • SHMT or CBS first? | Phoenix Rising ME CFS Forums
    Should one address CBS before SHMT? I've been taking SHMT spray for about a month and initially didn't seem to have any negative effects from it But now that my sulfur ammonia levels have increased, it seems that just half a dose of the SHMT spray may be causing some detox effects Does
  • Rich------Suggestions for CBS Mutation - Phoenix Rising ME CFS Forums
    But then, I don't have the ACAT or SHMT either and those two are bigger issues to deal with then the CBS I would be leery about guessing what your blocks are and then treating them If you can afford even one of the gene tests, I'd get it done HI Greenshots Sounds like you have come along way Good for you
  • Help with interpreting please! | Phoenix Rising ME CFS Forums
    On the methylation SNPs, you have a couple of First Priority mutations which are SHMT and CBS For SHMT take folinic acid For CBS, if it's expressed, you may have trouble tolerating methyl supplements and get a stress anxiety reaction or a head pressure If this is the case, you'll need to do a CBS protocol first so you can tolerate methyl supps You have a mutation on the major CBS gene and
  • DISCUSSION: Has anyone had massive improvement by moving to a low . . .
    Has anyone with CFS moved from a high humidity climate to a low-humidity climate like a desert climate and experienced remission or massive improvement in symptoms that lasted for over a year?





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