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  • Review - ScienceDirect
    These findings underscore the need for prospective, patient-centered studies in VEXAS syndrome This review supports the systematic integration of PROs in future research and provides insights to inform possible PRO assessment strategies International efforts are needed to rapidly accumulate knowledge on health-related quality of life and symptoms of patients with VEXAS syndrome
  • Exploring patient-reported outcomes and morbidity burden of patients . . .
    A scoping review conducted via PubMed (last updated September 2024) identified studies involving VEXAS patients, excluding studies primarily addressing hematologic adverse events or laboratory parameters, with no lower date restriction A double-review process was applied from screening to data charting Outcomes included the prevalence of manifestations of VEXAS-related morbidity burden and
  • Exploring patient-reported outcomes and morbidity burden of patients . . .
    We aimed to gather current knowledge on patient-reported outcomes (PRO) and morbidity burden of VEXAS patients Methods: A scoping review conducted via PubMed (last updated September 2024) identified studies involving VEXAS patients, excluding studies primarily addressing hematologic adverse events or laboratory parameters, with no lower date
  • Clinical features and treatments of VEXAS syndrome in . . . - Springer
    Conclusion This review revealed the lack of systematically analyzed studies focusing on VEXAS syndrome in the critical care setting, suggesting a significant gap in understanding the clinical characteristics and optimal treatments for VEXAS syndrome
  • Exploring patient-reported outcomes and morbidity burden of patients . . .
    METHODS: A scoping review conducted via PubMed (last updated September 2024) identified studies involving VEXAS patients, excluding studies primarily addressing hematologic adverse events or laboratory parameters, with no lower date restriction A double-review process was applied from screening to data charting Outcomes included the prevalence of manifestations of VEXAS-related morbidity
  • Patient Reported Outcomes in Vexas Syndrome - American Society of . . .
    Many studies have reported the increased mortality risk in VEXAS, but data are lacking regarding patient reported outcomes (PRO) in this highly morbid disease We aimed to study the quality of life and symptom burden in VEXAS patients seen at National Institutes of Health and correlate results with disease phenotype and outcomes
  • VEXAS: A review of current understandings and emerging . . . - Frontiers
    This review synthesises recent genetic, cellular, and clinical advances to consider VEXAS as an age-related proteosomopathy that unites clonal haematopoiesis with innate-immune dysregulation and provides appraisal of both established immunomodulators and emerging clone-directed therapies in addition to advocating harmonised response criteria
  • Improving outcomes in VEXAS syndrome: the need for prospective data
    These results confirm a previous study reporting that VEXAS syndrome is associated with a high incidence of serious infections especially in older patients carrying the p Met41Val mutation and treated with JAK inhibitors, and re-establish the high rate of complications and potential need for prophylaxis even in untreated disease [13]
  • Articles Research – VEXAS Foundation
    The material contained in these articles is provided for general information and educational purposes only Only your healthcare professional can address concerns and questions you may have about VEXAS syndrome
  • Management and Prognosis of VEXAS Syndrome
    The following is a summary of “Clinical features and treatments of VEXAS syndrome in critical care: a scoping review,” published in the April 2025 issue of Critical Care by Satoh et al Vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome was recently identified as a





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