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  • Micro-environment triple-responsive hyaluronic acid hydrogel dressings . . .
    In this work, we develop injectable hydrogels that are responsive to acidic conditions, reactive oxygen species (ROS), and high glucose levels in a diabetic wound micro-environment to sustainably deliver tannic acid (TA) to augment antibacterial, anti-inflammatory, and anti-oxidative activities
  • Micro-environment triple-responsive hyaluronic acid hydrogel . . .
    In this work, we develop injectable hydrogels that are responsive to acidic conditions, reactive oxygen species (ROS), and high glucose levels in a diabetic wound micro-environment to sustainably deliver tannic acid (TA) to augment antibacterial, anti-inflammatory, and anti-oxidative activities
  • RSC Publishing
    SN - 2050-750X DO - 10 1039 D4TB00261J M3 - 10 1039 D4TB00261J UR - http: dx doi org 10 1039 D4TB00261J Strategies targeting the diabetic micro-environment have been developed to promote wound healing However, it remains challenging to reverse the adverse conditions and re-activate tissue regeneration and angiogenesis
  • 一种具有三重触发按需释放功能的智能水凝胶平台,用于加速 . . .
    探索超能文献,一款革命性的AI驱动医学文献搜索引擎。使用先进的大语言模型和NLP技术,Suppr能够理解复杂的医学查询,并从海量文献中快速定位到您所需的研究。体验中文搜索的便捷,告别传统PubMed语法,一键生成思维导图,轻松下载参考文献。
  • Micro-environment triple-responsive hyaluronic acid hydrogel dressings . . .
    In this work, we develop injectable hydrogels that are responsive to acidic conditions, reactive oxygen species (ROS), and high glucose levels in a diabetic wound micro-environment to sustainably deliver tannic acid (TA) to augment antibacterial, anti-inflammatory, and anti-oxidative activities
  • lt;br hidden= gt;微环境三重反应性透明质酸水凝胶敷料,促进 . . .
    在这项工作中,我们开发了对糖尿病伤口微环境中的酸性条件、活性氧 (ROS) 和高葡萄糖水平做出反应的可注射水凝胶,以可持续地递送单宁酸 (TA) 以增强抗菌、抗炎和抗氧化活性。 这种三重响应机制是通过引入动态酰腙和苯基硼酯键来交联修饰的透明质酸 (HA) 链来设计的。 在糖尿病伤口中,酰腙键可以在低 pH 值下水解。 同时,葡萄糖可能与 TA 竞争,ROS 可能会氧化 C-B 键以释放 TA。 因此,TA 的持续释放是由糖尿病微环境触发的。 释放的 TA 有效清除 ROS 并杀死细菌。 糖尿病小鼠的体内实验表明,水凝胶敷料高度促进血管生成和细胞外基质(ECM)沉积,最终导致糖尿病皮肤伤口完全愈合。 这种微环境触发的三重反应药物释放为慢性糖尿病伤口愈合提供了一种有前途的方法。
  • api. crossref. org
    B"],"abstract":"pH\ ROS\ glucose triple-responsive OAH@TA hydrogel elicits controlled TA release, enhancing antibacterial, anti-inflammatory, and antioxidative properties to facilitate diabetic wound healing \ jats:p>","DOI":"10 1039\ d4tb00261j","type":"journal-article","created":{"date-parts":[[2024,4,10]],"date-time":"2024-04-10T14:00:45Z
  • Micro-environment triple-responsive hyaluronic acid hydrogel dressings . . .
    In this work, we develop injectable hydrogels that are responsive to acidic conditions, reactive oxygen species (ROS), and high glucose levels in a diabetic wound micro-environment to sustainably deliver tannic acid (TA) to augment antibacterial, anti-inflammatory, and anti-oxidative activities
  • 2024 Journal of Materials Chemistry B HOT Papers Home
    A biodegradable HCSL nanoreactor was constructed by the in situ encapsulation of 10-hydroxycamptothecin into a calcium sulfite nanocarrier and then modifying liposomes for tumor-enhanced SO 2 gas therapy in combination with chemotherapy
  • Micro-environment triple-responsive hyaluronic acid hydrogel . . .
    已经有人上传了文献,该状态下其他人无法上传,请等待求助人确认该文件是否是他需要的。 如果求助人在 48 小时内还未确认,系统默认应助成功,本求助将自动关闭。 温馨提示:本文件中的下载单位、IP等隐私信息已被删除。 如有遗漏,请 提交工单 反馈。





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